Structural biologist

Job Description:
• We are seeking a highly skilled and motivated Structural Biologist to join our drug
discovery programs. The ideal candidate will bring deep expertise in
macromolecular structure determination and modeling, with a focus on elucidating
protein structures, analyzing ligand binding, and driving rational drug design in
collaboration with computational and medicinal chemistry teams.
Key Responsibilities:
• Analyze protein-ligand interactions to inform medicinal chemistry and lead
optimization efforts.
• Conduct molecular dynamics (MD) simulations and free energy calculations to
evaluate complex stability and binding energetics.
• Apply structural insights to guide hit-to-lead and lead optimization strategies.
• (Preferred) Utilize machine learning models to support binding site prediction or
compound prioritization.
Required Skills & Experience:
• Strong expertise in structural biology techniques, such as crystallography, cryo-<...